Day One: Protein Mechanics

Morning Session: Protein Mechanics and Dynamic Force Spectroscopy

8:00 am to 8:45 amBreakfast - Continental Breakfast served in CNSI Lobby
8:45 am to 9:00 am Workshop welcome and overview, A. Levine
9:00 am to 10:00 am Dynamic Force Spectroscopy, K. Ritchie (Purdue)
10:00 am to 11:00 am Theory of Dynamic Force Spectroscopy of Protein Ligand Bonds, R. Bruinsma (UCLA)
11:00 am to 12:00 pm

Discussion: Mechanochemistry and the Challenges of Probing Protein Mechanics, led by Ritchie and Bruinsma

12:00 pm to 1:00 pm Lunch - Sandwiches provided in the CNSI lobby

Afternoon Session: Protein Mechanics and Allostery

1:00 pm to 2:00 pm

Entropic Allostery, T. McLeish (Durham)

2:00 pm to 3:00 pm Exploiting Cooperativity and Allosteric Control to Build Better Biosensors, K. Plaxco (UCSB)
3:30 pm to 3:30 pm Break: Coffee and cookies provided in the CNSI lobby
3:30 pm to 5:00 pm

Discussion: Entropy vs Energy in Allostery? Discussion Leaders: McLeish and Plaxco

5:00 pm to 6:30 pmDinner: In Westwood
6:30 pm to 8:00 pm Poster Session: In CNSI Lobby